大漠之上，镖人、官府、西域五大家族等多方势力盘根错节、暗潮涌动。“天字第二号逃犯”刀马接下特殊押镖任务，和同伴一起从西域护镖远赴长安。不料，他们的护送对象竟是“天字第一号逃犯”知世郎……天下熙熙皆为利来，各方势力闻风入局，抢镖厮杀接连上演……
Wu Jing
Dao Ma
Nicholas Tse Ting-Fung
Di Ting
Chen Lijun
Ayuya
Yu Shi
Shu
Sun Yizhou
Zhishilang
Li Yunxiao
Ms. Yanzi
Ju Qianlang
Xiao Qi
Ci Sha
Heyi Xuan
Tony Leung Ka-fai
Old Mo
Max Zhang
Double-headed Snake
Jet Li
Lord Chang
Kara Hui Ying-Hung
Mrs. Yuchi
Zhang Yi
Pei Shiju
Liu Yaowen
Pei Xingyan
