第二部仍以女孩凯蒂和她的姨妈珍玛为主线，她们遭到了下一代机器人“艾米莉亚”的疯狂攻击，而本已沦为智能语音助手的梅根，似乎是帮助她们对抗艾米莉亚的绝佳选择。
Allison Williams
Gemma
Amie Donald
M3GAN
Violet McGraw
Cady
Jenna Davis
M3GAN (voice)
Brian Jordan Alvarez
Cole
Jen Van Epps
Tess
Aristotle Athari
Christian Bradley
Ivanna Sakhno
AMELIA
Timm Sharp
Agent Tim Sattler
Jemaine Clement
Alton Appleton
Mayen Mehta
Naveen Tripathi
Mark Mitchinson
Niles Keller
Fryda Wolff
Moxie (voice)
Luke Hawker
Agent Murphy
