Larnell、Luanne带着他们的疯狂搞笑再次回归，由于吸烟引起的怪异副作用，他们前往南美寻求治疗。在深山丛林里，他们遇到了致命的危险……
Brett Chukerman
Allistair
Mitch Eakins
Bachman
John Patrick Jordan
Larnell
Brian Lloyd
Brett
Amy Paffrath
Velicity
Robin Sydney
Luann
Sonny Carl Davis
Rabbit
Jacob Witkin
Cyril
Michael Shepperd
King Bong (Voice)
Michelle Mais
Evil Bong / Eebee (voice)
August Knight
Poontang Tribe
Ariel X.
Kyle Stone
Emilianna
