传奇狗肖立志学会说话后并不满足，它希望能够成为一个真正的男孩，在伊万教授的帮助下，通过DNA的转变，肖立志获得了人类的思维和性格……
Nathan Lane
Spot Helperman / Scott Leadready II / Scott Manly-Manning (voice)
Kelsey Grammer
Dr. Ivan Krank (voice)
Shaun Fleming
Leonard Amadeus Helperman (voice)
Debra Jo Rupp
Mrs. Mary Lou Moira Angela Darling Helperman (voice)
David Ogden Stiers
Mr. Jolly (voice)
Jerry Stiller
Pretty Boy (voice)
Paul Reubens
Dennis (voice)
Megan Mullally
Adele (voice)
Wallace Shawn
Principal Crosby Strickler (voice)
Rob Paulsen
Ian Wazselewski (voice)
Jay Thomas
Barry Anger (voice)
Estelle Harris
Mrs. Boogin (voice)
Genie Francis
Marsha / Marcia (voice)
Anthony Geary
John / Juan (voice)
