一名羞怯内向但对实验充满热忱的脑科医生，对院内一群沉睡三，四十年的脑部疾病患者大胆用药，结果奇迹似的使病人于一夕之间苏醒，重新体验生命中的悲喜。受到鼓舞的医生亦试著和病人交往。未料新药效果无法持续，使得病人再度沉睡。
Robert De Niro
Leonard Lowe
Robin Williams
Malcolm Sayer
John Heard
Dr. Kaufman
Julie Kavner
Eleanor Costello
Penelope Ann Miller
Paula
Ruth Nelson
Mrs. Lowe
Max von Sydow
Peter Ingham
Anne Meara
Miriam
Dexter Gordon
Rolando
George Martin
Frank
Alice Drummond
Lucy Fishman
Richard Libertini
Sidney
Laura Esterman
Lolly
Barton Heyman
Bert
