John Cusack
Igor (voice)
Myleene Klass
Dr. Holzwurm (voice)
Robin Walsh
Dr. Holzwurm's Igor (voice)
Matt McKenna
Dr. Herzschlag (voice)
John Cleese
Dr. Glickenstein (voice)
Steve Buscemi
Scamper (voice)
Sean Hayes
Brain (voice)
Suzy Eddie Izzard
Dr. Schadenfreude (voice)
Jay Leno
King Malbert (voice)
Jennifer Coolidge
Jaclyn / Heidi (voice)
Molly Shannon
Eva (voice)
James Lipton
Himself
Christian Slater
Dr. Schadenfreude's Igor (voice)
Arsenio Hall
Carl Cristall (voice)
