Storm Reid
Meg Murry
Oprah Winfrey
Mrs. Which
Reese Witherspoon
Mrs. Whatsit
Mindy Kaling
Mrs. Who
Levi Miller
Calvin O'Keefe
Deric McCabe
Charles Wallace Murry
Chris Pine
Dr. Alex Murry
Gugu Mbatha-Raw
Dr. Kate Murry
Zach Galifianakis
The Happy Medium
Rowan Blanchard
Veronica Kiley
Michael Peña
Red
André Holland
Principal Jenkins
Bellamy Young
Camazotz Woman
David Oyelowo
The It (voice)
