Kate Higgins
Frankie Stein / Lilith Van Helscream (voice)
Cindy Robinson
Jackson Jekyll / Holt Hyde / Operetta / Additional Voice (voice)
Salli Saffioti
Clawdeen Wolf / Cleo de Nile (voice)
Erin Fitzgerald
Abbey Bominable / C.A. Cupid / Clair / Additional Voices (voice)
Laura Bailey
Lagoona Blue / Headmistress Bloodgood (voice)
Debi Derryberry
Draculaura (voice)
Ogie Banks
Clawd Wolf (voice)
Evan Smith
Deuce Gorgon / Gil Webber / Thad (voice)
America Young
Howleen Wolf / Toralei Stripe (voice)
Audu Paden
Ghoulia Yelps / Manny Taur / Sheriff / Additional voices (voice)
Cam Clarke
Heath Burns / Mr. Rotter / Goon #2 (voice)
Julie Maddalena
Robecca Steam / Venus McFlytrap (voice)
Steve Staley
Chad / Kid #1 (voice)
Mark Mercado
Gargoyle (voice)
