Debi Derryberry
James 'Jimmy' Isaac Neutron (voice)
Megan Cavanagh
Judy Neutron / VOX (voice)
Mark DeCarlo
Hugh Neutron / Pilot / Arena Guard (voice)
Jeffrey Garcia
Sheen Estevez (voice)
Patrick Stewart
King Goobot V (voice)
Martin Short
Ooblar (voice)
Frank Welker
Goddard / Poultra (voice)
Rob Paulsen
Carl Wheezer / Mr. and Mrs. Wheezer / Kid in Classroom (voice)
Carolyn Lawrence
Cindy Vortex (voice)
Crystal Scales
Libby Folfax (voice)
Candi Milo
Nick Dean / Britney / PJ (voice)
David L. Lander
Yokian Guard / Gus (voice)
Carlos Alazraqui
Mr. Estevez (voice)
Jim Cummings
Ultra Lord / Mission Control / General Bob (voice)
