Eddie Murphy
Dr. John Dolittle
Kristen Wilson
Lisa Dolittle
Kyla Pratt
Maya Dolittle
Raven-Symoné
Charisse Dolittle
Steve Zahn
Archie (voice)
Lisa Kudrow
Ava (voice)
James Avery
Eldon
Andy Richter
Eugene Wilson
Lil' Zane
Eric
Denise Dowse
Secretary
Elayn J. Taylor
Eldon's Wife
Kevin Pollak
Riley / Alligator
Victor Raider-Wexler
Judge B. Duff
Jeffrey Jones
Joe Potter
